Wake County is home to employers of all industries and sizes. The Major Employers List below provides a snapshot of both public and private companies in Wake County and Research Triangle Park that employ 2.000 or more people.
The complete Major Employers Directory, which contains companies located in Wake County and the Research Triangle Park that employ more than 250 people, can be viewed here.
| Employers | # Employees |
| Duke University and Duke Health Systems | 43,108 |
| State of North Carolina | 24,083 |
| Wake County Public School System | 17,000 |
| Wal-Mart | 16,800 |
| University of North Carolina At Chapel Hill | 12,204 |
| WakeMed Health & Hospitals | 10,307 |
| Food Lion | 9,037 |
| North Carolina State University | 9,019 |
| IBM (International Business Machines) | 9,000 |
| Target Stores | 8,400 |
| UNC Rex Healthcare System | 7,700 |
| Fidelity Investments | 5,968 |
| Harris Teeter | 5,300 |
| Lenovo | 5,100 |
| Cisco Systems | 5,000 |
| Wake County Government | 4,389 |
| SAS Institute, Inc. | 4,024 |
| City of Raleigh | 3,974 |
| Pfizer | 3,700 |
| Sensus (a Xylem Brand) | 3,691 |
| Blue Cross and Blue Shield North Carolina | 3,583 |
| Conduent Business Services | 3,487 |
| Epic Games | 3,118 |
| Metlife | 3,100 |
| Wells Fargo | 2,965 |
| Lowe's Home Centers | 2,750 |
| Duke Energy | 2,743 |
| Iqvia | 2,700 |
| Wake Technical Community College | 2,547 |
| Cree | 2,500 |
| Wolfspeed | 2,500 |
| Credit Suisse | 2,373 |
| Research Triangle Institute (RTI) | 2,370 |
| First Citizens Bancshares | 2,200 |
| Grifols | 2,100 |
| Syneos Health | 2,100 |
| bioMérieux | 2,000 |
| Pharmaceutical Product Development (PPD) | 2,000 |
| Red Hat | 2,000 |
| Siemens | 2,000 |
| United States Postal Service | 2,000 |
| Verizon Business Network Services | 2,000 |